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Dojindo Labs
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MedChemExpress
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Danaher Inc
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Beyotime
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Selleck Chemicals
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Santa Cruz Biotechnology
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TargetMol
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Cayman Chemical
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Biomax Inc
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Nacalai
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LabForce AG
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Abbkine Inc
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Image Search Results
Journal: Frontiers in Oral Health
Article Title: Novel small molecule targeting PgQC reduces Porphyromonas gingivalis virulence
doi: 10.3389/froh.2026.1716188
Figure Lengend Snippet: S-0636 exhibits a low potential of cytotoxicity in human cell lines. Human liver cells (HepG2, black bars), human embryonic kidney cells (HEK293, grey bars), human gingival keratinocytes (hTERT-TIGK, dark grey bars), and human gingival fibroblasts (hTERT-TIGF, light gray bars) were seeded and cultivated as described above. Once the cells reached ∼80% confluency, the medium was replaced with fresh medium containing various concentrations of S-0636, followed by an additional 24-hour incubation under the same conditions. The WST-8 assay determined the viability of cells. Cells treated with 0.1% Triton X-100 served as a negative control), while cells treated with the S-0636 compound diluent served as a positive control. Cell viability was quantified by measuring the absorbance of WST-8 formazan at 450 nM using a Tecan Sunrise microplate reader. All experiments were performed in at least three independent biological replicates.
Article Snippet: After treatment,
Techniques: Incubation, Negative Control, Positive Control